• Development of fit-for-purpose bioanalytical/drug metabolism/pharmacokinetics platforms for monoclonal antibodies, antibody-drug conjugates (ADCs), and small molecules for lead optimization stage and beyond.
• Drug development using Accelerator Mass Spectrometer (AMS) and 14C-microtracer for absolute bioavailability, mass balance, metabolite profiling/identification and bioequivalence studies.
• Development of in silico lead optimization process and human PK/metabolism prediction platforms.
• Method validation/qualification/fit-for-purpose assay development using various mass spectrometers for NMEs and clinical biomarkers
• Teaching courses:
- Clinical pharmacotherapy-I and III (topics: Oncology, CNS, COPD and Asthma) (undergraduate)
-Preclinical development and innovative IND strategy (graduate course)
-GCP and clinical drug development strategy (graduate course)
-Advance Antibody-Drug Conjugates – I and II (graduate course)
-In silico PBPK modeling using GastroPlus and lead optimization strategy (graduate program)
-Biotech entrepreneurship-I and II (undergraduate and graduate courses)
